Manual Instalacion Alarma Cobra 3860
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have been observed to bite outdoor at night, and so the minor nocturnal vector species, Anopheles funestus, may have been responsible for infecting the study participants. However, most malaria infections in western Kenya are caused by An. gambiae s.sp., with a strain carrying the K76T-R539T double haplotype observed only rarely. We therefore believe that most of the infections observed are due to An. gambiae s.s. The villages that we sampled were already under WHO recommended ITN scale up implementation in 2006. However, the study was not able to determine precisely whether the increase in ITN use is responsible for the decrease in CQ resistance. Further work is needed to determine whether the use of ITN is responsible for the reported decrease. If it is not, other factors, such as increased insecticide use for agricultural purposes or other interventions, may play a role.
However, we also observed a significant difference in SP resistance in the 3 PSS genotypes between the two study years. The frequency of the Sdhps-540 allele, which was previously associated with a protective effect [69,70], was significantly lower between 2001 and 2007 in the gemine area, where SP resistance was the highest in 2007 (36% in 2007 vs. 4% in 2001; p = 0.06). We also detected significantly higher prevalence of Fever on the day of malaria blood collection since past studies describe malaria to contribute significantly to febrile conditions during the non-rainy season [96]. d2c66b5586